Formerly known as SIDASOL, the association was co-founded by Liège University Hospital and the University of Liège in 2009. As a result, it has been able to establish completely free and anonymous HIV screening consultations. It has also developed outdoor screening using rapid diagnostic tests in locations frequented by key target audiences. Furthermore, it has formed valuable partnerships with associations and private businesses that cater to these key groups, enabling prevention and peer education initiatives. Centre S's primary mission is the prevention of HIV/AIDS, hepatitis, and other STIs through both primary and secondary prevention strategies.
In addition to their prevention efforts, the team conducts research, anti-discrimination work, and training activities while also developing solidarity initiatives for vulnerable groups.
Their wide-ranging missions include primary prevention, the provision of prevention and risk reduction materials, vaccination against hepatitis A/B and HPV, PrEP consultations, communication campaigns on HIV, hepatitis, and other STIs, as well as activities and workshops. They also offer psycho-sexual support and provide on-site screening for HIV, hepatitis, and other STIs, along with external screening for priority groups. The association also conducts training for (future) health professionals and volunteers.